Title : Transcriptional Enhancers – Looking out for the genes and each other
Speaker: Sridhar Hannenhalli, University of Maryland at College Park
Notes: http://www.marylandbiophysics.umd.edu/seminars/ Abstract : The ENCODE project, via generation of unprecedented transcriptomic and epigenomic profiles, has revealed a complex layer of transcriptional regulation mediated by distal regulatory enhancers distributed throughout the human genome. These data open up more questions than they answer. We will discuss their nuclear organization, how they can be used for better genotype-phenotype associations and their potential emergent properties by virtue of their spatial proximity.