Title:Â Â Scaling up quantum systems for clock and fundamental physics Abstract:Â Laser and quantum sciences have fueled revolutionary developments in atomic, molecular, and fundamental physics. Quantum state engineering and many-body physics provide coherent quantum systems at increasingly large sizes, revolutionizing the performance of clocks and promising new discovery opportunities. Quantum technology has brought many thousands of atoms to minute-long coherence, and employed entanglement for clock operations. We are also knocking on the door of nuclear physics, heralded by the recent breakthrough of quantum-state-resolved laser spectroscopy of thorium-229 nuclear transition. The broad scope of progress in quantum metrology provides new tools for quantum sensing, and raises the prospect of using quantum sensors to search for new physics and probe the interface of gravity and quantum mechanics.